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Mathematics in pharmacokinetics what and why a second attempt to make it clearer we have used equations for concentration c as a function of time t.
Pharmacokinetic definitions math. D dose dosing interval cl clearance vd volume of distribution ke elimination rate constant ka absorption rate constant f fraction absorbed bioavailability k0 infusion rate t duration of infusion c plasma concentration. Die pharmakokinetik ist ein teilbereich der pharmakologie und behandelt die effekte denen ein arzneimittel im organismus unterliegt. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Wiktionary 0 00 0 votes rate this definition.
The substances of interest include any chemical xenobiotic such as. Das entsprechende adjektiv lautet pharmakokinetisch. From these concentration time equations we can determine the elimination rate constant. The pharmacokinetic properties determine the onset intensity and the duration of drug action in body.
Pharmacokinetics is the study of a drug absorption distribution metabolism and elimination from the body. It show drug effect on body upon administration. Pharmaceutical drugs pesticides food additives cosmetics etc. Pharmacokinetic adjective of or to with pharmacokinetics.
The pharmacokinetic properties of a drug. Pharmacokinetics sometimes abbreviated as pk is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. Four processes encompass the pharmacokinetics of a medication. Die resorption die distribution der metabolismus sowie die elimination des arzneistoffs.
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